Urticaria pigmentosa
Urticaria pigmentosa teri mastositozining eng keng tarqalgan shaklidir. Bu teridagi mast hujayralarining haddan tashqari ko‘pligi tufayli yuzaga keladigan kam uchraydigan kasallik bo‘lib, tirnash xususiyati bilan terida ürtiker yoki yaralar paydo bo‘ladi. Qizil yoki jigarrang dog‘lar ko‘pincha terida, odatda ko‘krak, peshona va orqada ko‘rinadi. Mast hujayralari tirnash xususiyati (masalan, terini ishqalash, issiqlik ta’siri) bilan haddan tashqari ko‘p gistamin ishlab chiqaradi, bu esa tirnash xususiyati beruvchi hududda, ba’zan “Darier belgisi” deb ataladigan, lokalizatsiya qilingan uyalar paydo bo‘lishiga olib keladi.
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Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
Odatda yosh bolalarda tanada paydo bo‘ladi.
relevance score : -100.0%
ReferencesMastocytosis - teri, suyak iligi va ovqat hazm qilish tizimi kabi tananing turli qismlarida ko'plik mast hujayralari mavjud bo'lgan holat. Jahon sog'liqni saqlash tashkiloti (JSST) ma'lumotlariga ko'ra, cutaneous mastocytosis uchta asosiy turga bo'linadi. Birinchi tur (mastocytomas) – soliter yoki bir nechta (≤3) lezyonlardan iborat. Ikkinchi tur (urticaria pigmentosa) ko'plik lezyonlarni o'z ichiga oladi, odatda 10 dan ortiq, 100 dan kamroq. Oxirgi tur teri bo'ylab keng tarqalgan ishtirokini ko'rsatadi. Urticaria pigmentosa – bolalarda teri mastositozining eng keng tarqalgan shakli, ammo kattalarda ham paydo bo'lishi mumkin. Bu odatda o'smirlik davrida yaxshilanadigan zararsiz holat. Katta yoshdagi mastositozdan farqli o'laroq, urticaria pigmentosa kamdan‑kam hollarda ichki organlarga ta'sir qiladi. Urticaria pigmentosaning o'ziga xos xususiyatlaridan biri – terida mayda, qichishuvchi, qizil‑jigarrang yoki sarg'ish‑jigarrang dog'lar yoki lezyonlar paydo bo'ladi, odatda ürtiker deb ataladi. Bu dog'lar odatda bolalikda paydo bo'ladi va hayot davomida davom etishi mumkin.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
6 yoshli qizaloq bosh terisida birinchi marta dog‘lar paydo bo‘lgandan so‘ng, oxirgi olti oy ichida yuzi va tanasiga tarqalgan bir necha quyuq rangli dog‘lar bilan keldi. Bosim qo‘llanganda bu dog‘lar ko‘tarilib, qizarib, qichishdi. Qizaloq qizarish, qusish, diareya yoki xirillashni boshdan kechirmadi; shaxsiy va oilaviy tibbiy tarixi haqida ma'lumot bermadi. Tekshiruvda bosh terisi, peshonasi, yuzi, bo‘ynida bir necha qora dog‘lar, ko‘krak va orqa tomonida biroz ko‘tarilgan qora dog‘lar topildi. Dog‘larni engil ishqalash 2 daqiqada shishib, qichishishga olib keldi, ammo alomatlar 15‑20 daqiqada yo‘qoldi (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
